Updated Jan 29, 2026
Stoke Therapeutics Leases 98,500 Square Feet Office At 245 Fifth Avenue Waltham MA
245 Fifth Avenue
Building Size
98,500 SF
Asset Type
Office
Closing
Jan 27, 2026
About this deal
AI
The property asset involved in the transaction is an office space located at 245 Fifth Avenue in Waltham, MA, encompassing a total area of 98,500 square feet. The transaction is part of the commercial real estate market, specifically focused on office assets.
Summary of transaction details:
- Property Type: Office
- Transaction Amount: Not Disclosed
- Address: 245 Fifth Avenue
- Market: Waltham, MA
- Landlord: Anchor Line Partners
- Tenant: Ian F. Smith - Stoke Therapeutics
- Brokers: Mitch Perez, Connor Barnes & Michael Weiss - Cushman & Wakefield
The long-term lease signed by Stoke Therapeutics was aimed at relocating from Bedford to enhance its capabilities for commercializing its first potential medicine targeting Dravet syndrome. It also reflects the organization's intent to expand its research pipeline.
On the Map
Office
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Waltham Office Market Snapshot
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Purchase Price
Annual NOI
Loan Amount
Interest Rate (%)
Loan Term (yrs)
Down Payment (%)
Cap Rate
5.80%
Cash-on-Cash
-1.66%
Monthly Payment
$14,164
Annual Debt Svc
$169,964
Annual Cash Flow
$-11,334
DSCR
0.93