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245 Fifth Avenue

Stoke Therapeutics Leases 98,500 Square Feet Office At 245 Fifth Avenue Waltham MA
LEASEDOffice

Stoke Therapeutics Leases 98,500 Square Feet Office At 245 Fifth Avenue Waltham MA

245 Fifth Avenue

Building Size

98,500 SF

Asset Type

Office

Closing

Jan 27, 2026

AI

The property asset involved in the transaction is an office space located at 245 Fifth Avenue in Waltham, MA, encompassing a total area of 98,500 square feet. The transaction is part of the commercial real estate market, specifically focused on office assets.

Summary of transaction details:

  • Property Type: Office
  • Transaction Amount: Not Disclosed
  • Address: 245 Fifth Avenue
  • Market: Waltham, MA
  • Landlord: Anchor Line Partners
  • Tenant: Ian F. Smith - Stoke Therapeutics
  • Brokers: Mitch Perez, Connor Barnes & Michael Weiss - Cushman & Wakefield

The long-term lease signed by Stoke Therapeutics was aimed at relocating from Bedford to enhance its capabilities for commercializing its first potential medicine targeting Dravet syndrome. It also reflects the organization's intent to expand its research pipeline.

Players

Michael Weiss

Douglas Elliman

Broker

$7.7M

vol

3 deals

Broker
Cushman & Wakefield
Cushman & WakefieldBrokerage
Anchor Line Partners
Anchor Line PartnersLandlord

Waltham Office Market Snapshot

Boundary boundary · Office · Lease transactions

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Purchase Price

Annual NOI

Loan Amount

Interest Rate (%)

Loan Term (yrs)

Down Payment (%)

Cap Rate

5.80%

Cash-on-Cash

-1.66%

Monthly Payment

$14,164

Annual Debt Svc

$169,964

Annual Cash Flow

$-11,334

DSCR

0.93